Epilepsy surgery in children and adults.

Details

Serval ID
serval:BIB_C89760C7474C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Epilepsy surgery in children and adults.
Journal
Lancet. Neurology
Author(s)
Ryvlin P., Cross J.H., Rheims S.
ISSN
1474-4465 (Electronic)
ISSN-L
1474-4422
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
13
Number
11
Pages
1114-1126
Language
english
Notes
Publication types: REVIEW Publication Status: ppublish Document Type: Review
Abstract
SUMMARY: Epilepsy surgery is the most effective way to control seizures in patients with drug-resistant focal epilepsy, often leading to improvements in cognition, behaviour, and quality of life. Risks of serious adverse events and deterioration of clinical status can be minimised in carefully selected patients. Accordingly, guidelines recommend earlier and more systematic assessment of patients' eligibility for surgery than is seen at present. The effectiveness of surgical treatment depends on epilepsy type, underlying pathology, and accurate localisation of the epileptogenic brain region by various clinical, neuroimaging, and neurophysiological investigations. Substantial progress has been made in the methods of presurgical assessment, particularly in patients with normal features on MRI, but evidence is scarce for the indication and effect of most presurgical investigations, with no biomarker precisely delineating the epileptogenic zone. A priority for the development of epilepsy surgery is the generation of high-level evidence to promote the harmonisation and dissemination of best practices.
Pubmed
Web of science
Create date
02/12/2014 19:06
Last modification date
20/08/2019 16:43
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