Expectant management compared with elective delivery at 37 weeks for gastroschisis.

Details

Serval ID
serval:BIB_C7513914F371
Type
Article: article from journal or magazin.
Collection
Publications
Title
Expectant management compared with elective delivery at 37 weeks for gastroschisis.
Journal
Obstetrics and Gynecology
Author(s)
Baud D., Lausman A., Alfaraj M.A., Seaward G., Kingdom J., Windrim R., Langer J.C., Kelly E.N., Ryan G.
ISSN
1873-233X (Electronic)
ISSN-L
0029-7844
Publication state
Published
Issued date
2013
Volume
121
Number
5
Pages
990-998
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish. pdf type: Original Research
Abstract
OBJECTIVE: To estimate obstetric and neonatal outcomes after induction of labor at 37 weeks of gestation compared with expectant management in pregnancies complicated by fetal gastroschisis.
METHODS: The management of 296 pregnancies involving fetal gastroschisis (1980-2011) was reviewed from a single perinatal center. Ultrasound surveillance and nonstress testing were performed every 2 weeks from 30 weeks of gestation, weekly from 34 weeks of gestation, and twice weekly after 35 weeks of gestation until delivery. Labor was induced if fetal well-being testing was abnormal and, since 1994, labor was routinely induced at 37 weeks of gestation.
RESULTS: Of 153 pregnancies reaching 37 weeks of gestation, labor was induced in 77 (26%) and 76 (25.7%) were allowed to labor spontaneously. There were no significant differences in mean maternal age (22 years in both), parity (56% compared with 66% nulliparous), presence of other fetal anomalies (12% compared with 9%), cesarean delivery rate (20% in both), 5-minute Apgar score less than 7 (10% compared with 12%), meconium at birth (36% compared with 49%), or respiratory distress syndrome (16% compared with 7%) between the induced and expectantly managed groups. However, neonatal sepsis (25% compared with 42%; P=.02) and a composite outcome of neonatal death and bowel damage (necrosis, atresia, perforation, adhesion; 8% compared with 21%; P=.02) were more common in expectantly managed pregnancies. Moreover, time to oral feeds (-3.4 days), time on total parenteral nutrition (-6.2 days), and hospital stay (-6.7 days) were reduced when labor was induced.
CONCLUSION: In fetuses with gastroschisis, induction of labor at 37 weeks of gestation was associated with reduced risks of sepsis, bowel damage, and neonatal death compared with pregnancies managed expectantly beyond 37 weeks of gestation.
LEVEL OF EVIDENCE: II.
Keywords
Female, Gastroschisis/complications, Gestational Age, Humans, Infant, Newborn, Infant, Newborn, Diseases/epidemiology, Infant, Newborn, Diseases/etiology, Labor, Induced, Pregnancy, Pregnancy Outcome, Retrospective Studies, Young Adult
Pubmed
Web of science
Create date
28/01/2014 15:39
Last modification date
20/08/2019 15:42
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