Merkel cells and the individuality of friction ridge skin

Details

Serval ID
serval:BIB_C6E9752E0595
Type
Article: article from journal or magazin.
Collection
Publications
Title
Merkel cells and the individuality of friction ridge skin
Journal
Journal of Theoretical Biology
Author(s)
Kücken M., Champod C.
ISSN
0022-5193 ; 1095-8541
ISSN-L
0022-5193
Publication state
Published
Issued date
10/2012
Peer-reviewed
Oui
Volume
317
Pages
229-237
Language
english
Abstract
There is no definite theory yet for the mechanism by which the pattern of epidermal ridges on fingers,
palms and soles forming friction ridge skin (FRS) patterns is created. For a long time growth forces in
the embryonal epidermis have been believed to be involved in FRS formation. More recent evidence
suggests that Merkel cells play an important part in this process as well. Here we suggest a model for
the formation of FRS patterns that links Merkel cells to the epidermal stress distribution. The Merkel
cells are modeled as agents in an agent based model that move anisotropically where the anisotropy is
created by the epidermal stress tensor. As a result ridge patterns are created with pattern defects as
they occur in real FRS patterns. As a consequence we suggest why the topology of FRS patterns is indeed
unique as the arrangement of pattern defects is sensitive to the initial configuration of Merkel cells.
Keywords
Epidermal ridges , Mathematical model , Fingerprints , Merkel cells
Create date
14/11/2012 14:27
Last modification date
20/08/2019 16:42
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