Mood stability during acute stimulator challenge in Parkinson's disease patients under long-term treatment with subthalamic deep brain stimulation

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State: Public
Version: author
Serval ID
serval:BIB_C6C903ECD1B8
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Mood stability during acute stimulator challenge in Parkinson's disease patients under long-term treatment with subthalamic deep brain stimulation
Journal
Movement Disorders
Author(s)
Berney Alexandre, Panisset Michel, Sadikot Abbas F., Ptito Alain, Dagher Alain, Fraraccio Maria, Savard Ghislaine, Pell Marc, Benkelfat Chawki
ISSN
0885-3185
Publication state
Published
Issued date
2007
Peer-reviewed
Oui
Volume
22
Number
8
Pages
1093-1096
Language
english
Notes
Mention de responsabiblité : Berney A, Panisset M, Sadikot AF, Ptito A, Dagher A, Fraraccio M, Savard G, Pell M, Benkelfat C. SAPHIRID:61293
Abstract
Acute and chronic behavioral effects of subthalamic stimulation (STN-DBS) for Parkinson's disease (PD) are reported in the literature. As the technique is relatively new, few systematic studies on the behavioral effects in long-term treated patients are available. To further study the putative effects of STN-DBS on mood and emotional processing, 15 consecutive PD patients under STN-DBS for at least 1 year, were tested ON and OFF stimulation while on or off medication, with instruments sensitive to short-term changes in mood and in emotional discrimination. After acute changes in experimental conditions, mood core dimensions (depression, elation, anxiety) and emotion discrimination processing remained remarkably stable, in the face of significant motor changes. Acute stimulator challenge in long-term STN-DBS-treated PD patients does not appear to provoke clinically relevant mood effects. © 2007 Movement Disorder Society
Pubmed
Web of science
Create date
10/03/2008 11:24
Last modification date
20/08/2019 16:42
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