Mortality, complications and loss of pulmonary function after pneumonectomy vs. sleeve lobectomy in patients younger and older than 70 years.

Details

Serval ID
serval:BIB_C628F265280B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Mortality, complications and loss of pulmonary function after pneumonectomy vs. sleeve lobectomy in patients younger and older than 70 years.
Journal
Interactive Cardiovascular and Thoracic Surgery
Author(s)
Melloul E., Egger B., Krueger T., Cheng C., Mithieux F., Ruffieux C., Magnusson L., Ris H.B.
ISSN
1569-9285 (Electronic)
ISSN-L
1569-9285
Publication state
Published
Issued date
2008
Volume
7
Number
6
Pages
986-989
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Abstract
Retrospective single institution analysis of all patients undergoing sleeve lobectomy or pneumonectomy between 2000 and 2005. Seventy-eight patients underwent pneumonectomy (65 patients <70 years, 13 patients >70 years) and 69 sleeve lobectomy (50 patients <70 years, 19 patients >70 years). Pre-existing co-morbidity, surgical indication and induction therapy was similarly distributed between treatment by age-groups. In patients <70 years, pneumonectomy and sleeve lobectomy resulted in a 30-day mortality of 3% vs. 0 and an overall complication rate of 26% vs. 44%, respectively. In patients >70 years, pneumonectomy and sleeve lobectomy resulted in a 30-day mortality of 15% vs. 0 and an overall complication rate of 23% vs. 32%. In both age groups, pneumonectomy was associated with more airway complications (NS) and a significantly higher postoperative loss of FEV(1) than sleeve lobectomy (P<0.0001, P<0.03). Age per se did not influence the loss of FEV(1) and DLCO for a given type of resection. Sleeve lobectomy may have a therapeutic advantage over pneumonectomy in the postoperative course of elderly patients.
Keywords
Age Factors, Aged, Forced Expiratory Volume, Hospital Mortality, Humans, Lung/physiopathology, Lung/surgery, Pneumonectomy/adverse effects, Pneumonectomy/mortality, Pulmonary Surgical Procedures/adverse effects, Pulmonary Surgical Procedures/mortality, Respiratory Function Tests, Retrospective Studies, Risk Assessment, Time Factors, Treatment Outcome
Pubmed
Open Access
Yes
Create date
18/02/2009 10:16
Last modification date
20/08/2019 15:41
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