Radionuclide techniques for valvular regurgitant index: comparison in patients with normal and depressed ventricular function

Details

Serval ID
serval:BIB_C546D74B1247
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Radionuclide techniques for valvular regurgitant index: comparison in patients with normal and depressed ventricular function
Journal
Journal of Nuclear Medicine
Author(s)
Nicod  P., Corbett  J. R., Firth  B. G., Dehmer  G. J., Izquierdo  C., Markham, R. V., Jr. , Hillis  L. D., Willerson  J. T., Lewis  S. E.
ISSN
0161-5505 (Print)
Publication state
Published
Issued date
09/1982
Volume
23
Number
9
Pages
763-9
Notes
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Sep
Abstract
We compared contrast angiography with three techniques of quantitating valvular regurgitation from radionuclide ventriculograms in 70 patients: 45 with documented regurgitation graded 1-4+, and 25 without regurgitation. The radionuclide "regurgitant index" (ratio of L to R ventricular stroke counts) was measured from fixed end-diastolic regions of interest (method A), from separate end-diastolic and end-systolic regions of interest (method B), and from a "stroke-volume image" (method C). Sensitivities for detecting 1+ or more regurgitation were: method A = 57.8%, method B = 37.8% and method C = 62.2%. Sensitivities for detecting 2+ or more regurgitation were: method A = 74.2%, method B = 54.8%, and method C = 77.4%. All methods are greater than 97% specific. Interobserver coefficients of variability were: method A = 9.1%, method B = 19.2%, and method C = 5.4%. The sensitivity of each method was improved when left-ventricular ejection fractions were greater than 0.35. No method consistently differentiated between 2+, 3+, and 4+ valvular regurgitation.
Keywords
Angiography Aortic Valve Insufficiency/radiography/*radionuclide imaging Erythrocytes Female Heart Catheterization Humans Male Middle Aged Mitral Valve Insufficiency/radiography/*radionuclide imaging Stroke Volume Technetium/diagnostic use
Pubmed
Web of science
Create date
25/01/2008 14:00
Last modification date
20/08/2019 15:40
Usage data