Treatment of acute mountain sickness by simulated descent: a randomised controlled trial.
Details
Serval ID
serval:BIB_C4D95353DBB2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Treatment of acute mountain sickness by simulated descent: a randomised controlled trial.
Journal
British Medical Journal
ISSN
0959-8138 (Print)
ISSN-L
0959-535X
Publication state
Published
Issued date
1993
Peer-reviewed
Oui
Volume
306
Number
6885
Pages
1098-1101
Language
english
Abstract
To evaluate the therapeutic efficacy of a portable hyperbaric chamber for treatment of acute mountain sickness.
Controlled randomised trial over two mountaineering seasons.
High altitude research laboratory at 4559 m above sea level.
64 climbers with acute mountain sickness randomly allocated to different treatments.
One hour of treatment in the hyperbaric chamber at a pressure of 193 mbar or 20 mbar as control or bed rest.
Symptoms of acute mountain sickness before, immediately after, and 12 hours after treatment. Permitted intake of analgesic and antiemetic drugs in the follow up period.
Treatment with 193 mbar caused greater relief of symptoms than did control treatment or bed rest. During the 12 hour follow up period intake of analgesics was similar (58-80% of subjects in each group). Symptom scores had improved in all subjects after 12 hours with no significant differences between groups.
One hour of treatment with 193 mbar in a portable hyperbaric chamber, corresponding to a descent of 2250 m, leads to a short term improvement in symptoms of acute mountain sickness but has no beneficial long term effects attributable to pressurisation.
Controlled randomised trial over two mountaineering seasons.
High altitude research laboratory at 4559 m above sea level.
64 climbers with acute mountain sickness randomly allocated to different treatments.
One hour of treatment in the hyperbaric chamber at a pressure of 193 mbar or 20 mbar as control or bed rest.
Symptoms of acute mountain sickness before, immediately after, and 12 hours after treatment. Permitted intake of analgesic and antiemetic drugs in the follow up period.
Treatment with 193 mbar caused greater relief of symptoms than did control treatment or bed rest. During the 12 hour follow up period intake of analgesics was similar (58-80% of subjects in each group). Symptom scores had improved in all subjects after 12 hours with no significant differences between groups.
One hour of treatment with 193 mbar in a portable hyperbaric chamber, corresponding to a descent of 2250 m, leads to a short term improvement in symptoms of acute mountain sickness but has no beneficial long term effects attributable to pressurisation.
Keywords
Acute Disease, Adolescent, Adult, Altitude Sickness/therapy, Atmosphere Exposure Chambers, Decompression/instrumentation, Female, Humans, Hyperbaric Oxygenation, Male, Middle Aged, Mountaineering
Pubmed
Web of science
Create date
30/10/2017 15:31
Last modification date
20/08/2019 16:40
Usage data
