Polymicrobial vertebral osteomyelitis after oesophageal biopsy: a case report.

Details

Ressource 1Download: BIB_C4CACE45B170.P001.pdf (1228.34 [Ko])
State: Public
Version: author
Serval ID
serval:BIB_C4CACE45B170
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Polymicrobial vertebral osteomyelitis after oesophageal biopsy: a case report.
Journal
Bmc Infectious Diseases
Author(s)
Giger A., Yusuf E., Manuel O., Clerc O., Trampuz A.
ISSN
1471-2334 (Electronic)
ISSN-L
1471-2334
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
16
Number
1
Pages
141
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: epublish
Abstract
BACKGROUND: While most cases of polymicrobial vertebral osteomyelitis are secondary to hematogenous seeding, direct inoculation during spinal surgery and contiguous spread from adjacent soft tissue are also potential routes whereby pathogens may infect the spine.
CASE PRESENTATION: A 74 year-old man presented with an exacerbation of back pain after a fall. His past medical history included hepatocellular and oesophageal carcinoma. Three months earlier he had undergone an endoscopic biopsy of the oesophagus for routine follow-up of his oesophagus carcinoma. He also underwent a vertebroplasty due to suspected pathologic fracture. On admission to hospital, magnetic resonance imaging revealed an infiltrative process at the level of the 5th and 6th thoracic vertebrae. Blood cultures were positive for both Streptococcus mitis and Gemella morbillorum. During his course of antibiotic therapy he developed an abscess at the level of 8th thoracic vertebrae and culture of this abscess grew Candida albicans. He was treated with antibiotics and antifungal drugs and recovered fully.
CONCLUSION: Vertebral osteomyelitis may be caused by direct spread following an oesophageal procedure. Microbiological diagnosis is essential to target the specific pathogen, especially in cases of polymicrobial infection.
Keywords
Aged, Anti-Bacterial Agents/therapeutic use, Antifungal Agents/therapeutic use, Candida albicans/isolation & purification, Gemella/isolation & purification, Humans, Magnetic Resonance Imaging, Male, Osteomyelitis/diagnosis, Osteomyelitis/drug therapy, Spine/radiography, Streptococcus mitis/isolation & purification, Thoracic Vertebrae/microbiology
Pubmed
Web of science
Open Access
Yes
Create date
14/04/2016 16:41
Last modification date
20/08/2019 15:40
Usage data