Overview of the predictive value of quantitative 18 FDG PET in head and neck cancer treated with chemoradiotherapy.

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State: Public
Version: Author's accepted manuscript
Serval ID
serval:BIB_C4724EBB7453
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Overview of the predictive value of quantitative 18 FDG PET in head and neck cancer treated with chemoradiotherapy.
Journal
Critical reviews in oncology/hematology
Author(s)
Castelli J., De Bari B., Depeursinge A., Simon A., Devillers A., Roman Jimenez G., Prior J., Ozsahin M., de Crevoisier R., Bourhis J.
ISSN
1879-0461 (Electronic)
ISSN-L
1040-8428
Publication state
Published
Issued date
12/2016
Peer-reviewed
Oui
Volume
108
Pages
40-51
Language
english
Notes
Publication types: Review ; Journal Article
Publication Status: ppublish
Publication types: Journal Article ; Review

Abstract
18 F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) allows to quantify the metabolic activity of a tumor (glycolysis) and has become a reference tool in oncology for the staging, restaging, radiotherapy planning and monitoring response in many cancers. Quantitative analyses have been introduced in order to overcome some of the limits of the visual methods, allowing an easier and more objective comparison of the inter- and intra-patients variations. The aims of this review were to report available evidences on the clinical value of quantitative PET/CT parameters in HNC. Forty-five studies, for a total of 2928 patients, were analyzed. Most of the data available dealt with the intensity of the metabolism, calculated from the Standard Uptake Value (SUV). Metabolic Tumor Volume (MTV) was well correlated with overall survival and disease free survival, with a higher predictive value than the maximum SUV. Spatial distribution of metabolism and textural analyses seems promising.

Keywords
Chemoradiotherapy, Fluorodeoxyglucose F18, Glycolysis, Head and Neck Neoplasms/diagnostic imaging, Head and Neck Neoplasms/therapy, Humans, Positron Emission Tomography Computed Tomography
Pubmed
Create date
22/12/2016 14:23
Last modification date
20/08/2019 15:39
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