Embryo survival in the oviduct not significantly influenced by major histocompatibility complex social signaling in the horse

Details

Ressource 1Download: Jeannerat_et_al-2020-Scientific_Reports.pdf (1276.89 [Ko])
State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_C38AF953BBA7
Type
Article: article from journal or magazin.
Collection
Publications
Title
Embryo survival in the oviduct not significantly influenced by major histocompatibility complex social signaling in the horse
Journal
Scientific Reports
Author(s)
Jeannerat E., Marti E., Thomas S., Herrera C., Sieme H., Wedekind C., Burger D.
ISSN
2045-2322
Publication state
Published
Issued date
2020
Volume
10
Number
1
Language
english
Abstract
The major histocompatibility complex (MHC) influences sexual selection in various vertebrates. Recently, MHC-linked social signaling was also shown to influence female fertility in horses (Equus caballus) diagnosed 17 days after fertilization. However, it remained unclear at which stage the pregnancy was terminated. Here we test if MHC-linked cryptic female choice in horses happens during the first days of pregnancy, i.e., until shortly after embryonic entrance into the uterus and before fixation in the endometrium. We exposed estrous mares to one of several unrelated stallions, instrumentally inseminated them with semen of another stallion, and flushed the uterus 8 days later to test for the presence of embryos. In total 68 embryos could be collected from 97 experimental trials. This success rate of 70.1% was significantly different from the mean pregnancy rate of 45.7% observed 17 days after fertilization using the same experimental protocol but without embryo flushing. Embryo recovery rate was not significantly dependent on whether the mares had been socially exposed to an MHC-dissimilar or an MHC-similar stallion. these observations suggest that MHC-linked maternal strategies affect embryo survival mainly (or only) during the time of fixation in the uterus.
Pubmed
Open Access
Yes
Funding(s)
Swiss National Science Foundation / Projects / 31003A_182265
Create date
24/01/2020 9:20
Last modification date
30/01/2020 7:20
Usage data