Enzymes of yeast polyphosphate metabolism: structure, enzymology and biological roles.

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Version: Author's accepted manuscript
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Serval ID
serval:BIB_C26FD1A051C5
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Enzymes of yeast polyphosphate metabolism: structure, enzymology and biological roles.
Journal
Biochemical Society Transactions
Author(s)
Gerasimaitė R., Mayer A.
ISSN
1470-8752 (Electronic)
ISSN-L
0300-5127
Publication state
Published
Issued date
2016
Volume
44
Number
1
Pages
234-239
Language
english
Abstract
Inorganic polyphosphate (polyP) is found in all living organisms. The known polyP functions in eukaryotes range from osmoregulation and virulence in parasitic protozoa to modulating blood coagulation, inflammation, bone mineralization and cellular signalling in mammals. However mechanisms of regulation and even the identity of involved proteins in many cases remain obscure. Most of the insights obtained so far stem from studies in the yeast Saccharomyces cerevisiae. Here, we provide a short overview of the properties and functions of known yeast polyP metabolism enzymes and discuss future directions for polyP research.
Keywords
Acid Anhydride Hydrolases/chemistry, Acid Anhydride Hydrolases/metabolism, Polyphosphates/metabolism, Saccharomyces cerevisiae/enzymology
Pubmed
Create date
13/05/2016 9:11
Last modification date
30/11/2019 8:09
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