Neuroleptanesthesia: current status

Details

Serval ID
serval:BIB_C1D1E58C5092
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Neuroleptanesthesia: current status
Journal
Canadian Journal of Anaesthesia
Author(s)
Bissonnette  B., Swan  H., Ravussin  P., Un  V.
ISSN
0832-610X
Publication state
Published
Issued date
02/1999
Peer-reviewed
Oui
Volume
46
Number
2
Pages
154-68
Notes
Journal Article
Review --- Old month value: Feb
Abstract
PURPOSE: To review the current status and possible future of neuroleptanalgesia/anesthesia, techniques that may be nearly extinct. SOURCE: Articles from 1966 to present were obtained from the Current Science and Medline databases. Search terms include neurolepananalgesia/anesthesia, conscious sedation, droperidol, benzodiazepines, propofol, ketamine, and opioids. Information and abstracts obtained from meetings on this topic helped complete the collection of information. PRINCIPAL FINDINGS: Droperidol/fentanyl may still be clinically indicated in the management of surgical seizure therapy for electrocorticography. However, the high incidence of post-operative sedation and restlessness discourage its use for other surgical or diagnostic procedures. Many surgical interventions, once thought ideally suited for neuroleptic agents, now meet better success with newer medications. The use of midazolam and/or propofol, in association with newer opioids, provides ideal anesthetic combinations. CONCLUSION: The advantages of newer anesthetic agents have redefined the clinical indications for neuroleptanesthesia. In routine modern anesthesia, anxiolysis, sedation, and/or analgesia is better provided, with quicker recovery, by the new pharmacokinetic and pharmacodynamic characteristics of recent medications than by the neuroleptic component of neuroleptanesthesia.
Keywords
Adjuvants, Anesthesia/therapeutic use Analgesics, Opioid/therapeutic use Anesthetics, Dissociative/administration & dosage Anesthetics, Intravenous/administration & dosage Anti-Anxiety Agents/therapeutic use Antipsychotic Agents/*administration & dosage/therapeutic use Conscious Sedation/methods Droperidol/therapeutic use Fentanyl/administration & dosage Humans Ketamine/administration & dosage Midazolam/administration & dosage *Neuroleptanalgesia Propofol/administration & dosage
Pubmed
Web of science
Open Access
Yes
Create date
17/01/2008 16:19
Last modification date
20/08/2019 15:36
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