Schmerzlose, rotviolette Hautflecken unter Immunsuppression. [Painless, red-violet skin lesions during immunosuppression]

Details

Serval ID
serval:BIB_C1247A377594
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Schmerzlose, rotviolette Hautflecken unter Immunsuppression. [Painless, red-violet skin lesions during immunosuppression]
Journal
Therapeutische Umschau
Author(s)
Pfister  M., Vogt  B.
ISSN
0040-5930 (Print)
Publication state
Published
Issued date
09/1998
Volume
55
Number
9
Pages
583-5
Notes
Case Reports
English Abstract
Journal Article --- Old month value: Sep
Abstract
A patient with painless, bluish-red skin lesions under immunosuppressive treatment for kidney transplantation is presented. The clinical and histological diagnosis was Kaposi's sarcoma. This is a rare but serious complication in the immunocompromised patient. Human Herpes virus 8 (HHV 8) was recently found in the lesions from patients with Kaposi's sarcoma. This supports the important role of immunosuppression in the development of this tumor. Therapy consists of reduction or stopping of the immunosuppressive drugs which is usually followed by reduction in tumor mass. Local skin tumors can be treated with irradiation or laser therapy. In the case of lesions of visceral organs chemotherapeutic regimens consisting of vinicristine/bleomycin are indicated. New strategies aim to reduce the virus load with antiviral drugs or to inhibit the angiogenesis of this highly vascularized tumor.
Keywords
Biopsy Diagnosis, Differential *Herpesvirus 8, Human/isolation & purification Humans Immunosuppressive Agents/*adverse effects/therapeutic use Kidney Transplantation/*immunology Male Middle Aged Sarcoma, Kaposi/*chemically induced/immunology/pathology Skin/pathology Skin Neoplasms/*chemically induced/immunology/pathology
Pubmed
Create date
25/01/2008 13:03
Last modification date
20/08/2019 15:35
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