Cardiorespiratory effects of an inspiratory hold and continuous positive pressure ventilation in goats

Details

Serval ID
serval:BIB_C057154E08C0
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cardiorespiratory effects of an inspiratory hold and continuous positive pressure ventilation in goats
Journal
Intensive Care Medicine
Author(s)
Perez-Chada  R. D., Gardaz  J. P., Madgwick  R. G., Sykes  M. K.
ISSN
0342-4642 (Print)
Publication state
Published
Issued date
1983
Volume
9
Number
5
Pages
263-9
Notes
Journal Article
Research Support, Non-U.S. Gov't
Abstract
The cardiorespiratory effects of three different patterns of mechanical ventilation were compared in sixteen anaesthetized goats. Intermittent positive pressure ventilation (IPPV), with an inspiratory: expiratory (I:E) time ratio of 1:3, was compared with an inspiratory hold pattern (IPPVH), with an I:E ratio of 3:1, and with continuous positive pressure ventilation (CPPV) adjusted to produce the same mean airway pressure. In eight animals with normal lungs, IPPVH reduced VD/VT and PaCO2, but produced no changes in oxygenation. CPPV did not significantly alter the efficiency of gas exchange. In a further eight animals, with oleic acid-induced lung damage, both IPPVH and CPPV produced a decrease in both VD/VT and PaCO2. Qs/Qt was significantly reduced by both CPPV and IPPVH, but the effect was more marked with CPPV, and the PaO2 was significantly increased only by CPPV. The increased effectiveness of CPPV in increasing PaO2 in this model may have been due to the greater increase in end-expiratory lung volume produced by this pattern of ventilation.
Keywords
Adult Animals Carbon Dioxide Goats *Hemodynamic Processes Humans Infant, Newborn Oxygen/physiology Positive-Pressure Respiration/*methods *Respiration Respiration, Artificial/*methods
Pubmed
Web of science
Create date
28/01/2008 10:48
Last modification date
20/08/2019 15:34
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