Wie gross ist das Karzinom- und Rezidivrisiko nach gutartiger Mammabiopsie? [How great is the risk of cancer and recurrence following benign breast biopsy?]

Details

Serval ID
serval:BIB_BF4F643B3170
Type
Article: article from journal or magazin.
Collection
Publications
Title
Wie gross ist das Karzinom- und Rezidivrisiko nach gutartiger Mammabiopsie? [How great is the risk of cancer and recurrence following benign breast biopsy?]
Journal
Helvetica Chirurgica Acta
Author(s)
Ris  H. B., Niederer  U., Stirnemann  H., Doran  J. E., Zimmermann  A.
ISSN
0018-0181 (Print)
Publication state
Published
Issued date
01/1989
Volume
55
Number
5
Pages
541-4
Notes
English Abstract
Journal Article --- Old url value: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2715018 --- Old month value: Jan
Abstract
Four hundred and thirty-eight patients with biopsy-proven benign breast disease were followed annually in a prospective manner for 4-17 years, to analyze breast cancer risk, correlations with cancer development and recurrence during follow-up. Twelve breast cancers developed in 12 patients during follow-up, giving a 2.6 fold increased cancer risk over the reference population. No association was found between patients who developed cancer and those who did not with respect to the initial histologic feature (p = 0.9), the age at entry by decades (p = 0.4) and relative to menopause (p = 0.3), the presence of cysts (p = 0.5) or calcification (p = 0.2) in the biopsy specimen, a family history of breast cancer (p = 0.7) or the follow-up time (p = 0.9). Benign breast disease does not inevitably lead to recurrence. Moreover, 47% of the 438 patients never had any recurrence and were free of symptoms during follow-up, and 84% never required a further operation. We conclude that an aggressive approach to benign breast disease is not justified, for any type of lesion as defined in this report.
Keywords
Adenofibroma/pathology Biopsy Breast/pathology Breast Neoplasms/*pathology Female Fibrocystic Breast Disease/*pathology Follow-Up Studies Humans Lipoma/pathology Neoplasm Recurrence, Local/*pathology Risk Factors
Pubmed
Web of science
Create date
29/01/2008 13:00
Last modification date
20/08/2019 15:33
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