Comparative cardiovascular effects of drugs used for hypertension.
Details
Serval ID
serval:BIB_BE51FE907696
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Comparative cardiovascular effects of drugs used for hypertension.
Journal
Drugs
ISSN
0012-6667
Publication state
Published
Issued date
1990
Peer-reviewed
Oui
Volume
39 Suppl 1
Pages
32-8
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Review - Publication Status: ppublish
Abstract
Currently 4 classes of antihypertensive drugs - diuretics, beta-blockers, calcium channel blockers and angiotensin-converting enzyme (ACE) inhibitors - are most commonly used to treat hypertensive patients. Each class of drug has a distinctive cardiovascular pharmacodynamic profile and even within classes there exist agents with slightly different properties. The effects of the various drug classes on the heart and peripheral circulation, on the kidney and electrolyte metabolism, on the brain and on the renin-angiotensin system are now reasonably well described. Knowledge and understanding of these different cardiovascular effects are extremely important in order to adapt treatment to the needs of an individual patient. Furthermore, when combination therapy becomes necessary, the different cardiovascular aspects of the various drugs can be used to enhance antihypertensive efficacy and to attenuate adverse effects of separate compounds.
Keywords
Adrenergic beta-Antagonists, Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Calcium Channel Blockers, Cardiovascular System, Diuretics, Humans
Pubmed
Web of science
Create date
05/03/2008 16:41
Last modification date
20/08/2019 15:32