The Role of Metabolomics in Brain Metabolism Research.

Details

Serval ID
serval:BIB_BDF1E9B84B08
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Title
The Role of Metabolomics in Brain Metabolism Research.
Journal
Journal of Neuroimmune Pharmacology
Author(s)
Ivanisevic J., Siuzdak G.
ISSN
1557-1904 (Electronic)
ISSN-L
1557-1890
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
10
Number
3
Pages
391-395
Language
english
Abstract
This special edition of the Journal of Neuroimmune Pharmacology focuses on the leading edge of metabolomics in brain metabolism research. The topics covered include a metabolomic field overview and the challenges in neuroscience metabolomics. The workflow and utility of different analytical platforms to profile complex biological matrices that include biofluids, brain tissue and cells, are shown in several case studies. These studies demonstrate how global and targeted metabolite profiling can be applied to distinguish disease stages and to understand the effects of drug action on the central nervous system (CNS). Finally, we discuss the importance of metabolomics to advance the understanding of brain function that includes ligand-receptor interactions and new insights into the mechanisms of CNS disorders.
Pubmed
Create date
06/06/2016 21:21
Last modification date
20/08/2019 15:32
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