Pituitary neuroendocrine tumors: a model for neuroendocrine tumor classification.

Details

Serval ID
serval:BIB_BD70A9911DC9
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Pituitary neuroendocrine tumors: a model for neuroendocrine tumor classification.
Journal
Modern pathology
Author(s)
Asa S.L., Mete O., Cusimano M.D., McCutcheon I.E., Perry A., Yamada S., Nishioka H., Casar-Borota O., Uccella S., La Rosa S., Grossman A.B., Ezzat S.
Working group(s)
Attendees of the 15th Meeting of the International Pituitary Pathology Club, Istanbul October 2019
Contributor(s)
Asioli S., Bozkurt S.U., Comunoglu N., Cossu G., Earls P., Gazioglu N., Hickman R.A., Ikeda H., Manojlovic-Gacic E., Messerer M., Öz B., Pakbaz S., Roncaroli F., Saeger W., Turchini J., Yarman S.
ISSN
1530-0285 (Electronic)
ISSN-L
0893-3952
Publication state
Published
Issued date
09/2021
Peer-reviewed
Oui
Volume
34
Number
9
Pages
1634-1650
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
The classification of adenohypophysial neoplasms as "pituitary neuroendocrine tumors" (PitNETs) was proposed in 2017 to reflect their characteristics as epithelial neuroendocrine neoplasms with a spectrum of clinical behaviors ranging from small indolent lesions to large, locally invasive, unresectable tumors. Tumor growth and hormone hypersecretion cause significant morbidity and mortality in a subset of patients. The proposal was endorsed by a WHO working group that sought to provide a unified approach to neuroendocrine neoplasia in all body sites. We review the features that are characteristic of neuroendocrine cells, the epidemiology and prognosis of these tumors, as well as further refinements in terms used for other pituitary tumors to ensure consistency with the WHO framework. The intense study of PitNETs has provided information about the importance of cellular differentiation in tumor prognosis as a model for neuroendocrine tumors in different locations.
Pubmed
Web of science
Create date
25/05/2021 9:30
Last modification date
02/09/2021 6:40
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