Etude de la variation interlaboratoire du test de dépistage prénatal des défauts de fermeture du tube neural [Interlaboratory variation in the prenatal screening test for neural tube closing defects].
Details
Serval ID
serval:BIB_BD6D86462E25
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Etude de la variation interlaboratoire du test de dépistage prénatal des défauts de fermeture du tube neural [Interlaboratory variation in the prenatal screening test for neural tube closing defects].
Journal
Sozial- Und Präventivmedizin
ISSN
0303-8408 (Print)
ISSN-L
0303-8408
Publication state
Published
Issued date
1984
Volume
29
Number
4-5
Pages
207-208
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Publication types: English Abstract ; Journal Article In WOS under the title [Prenatal Alpha-Fetoprotein Screening For Open Neural-Tube Defects - Study of the Interlaboratory Variability]
Publication Status: ppublish
Publication types: English Abstract ; Journal Article In WOS under the title [Prenatal Alpha-Fetoprotein Screening For Open Neural-Tube Defects - Study of the Interlaboratory Variability]
Abstract
Early detection of neural-tude defects is possible by determining Alpha-fetoprotein (AFP) in maternal serum. 16'685 pregnant women were observed. Three methods for the determination of the "normal" range are compared. The first one, already used in similar studies, makes use of a constant multiple of the median. The other two ones make use of robust estimates of location and scale. Their comparison shows the interest of the robust methods to reduce the interlaboratory variability.
Keywords
Female, Humans, Laboratories/standards, Neural Tube Defects/diagnosis, Pregnancy, Prenatal Diagnosis/methods, Switzerland, alpha-Fetoproteins/analysis
Pubmed
Web of science
Create date
08/09/2011 23:56
Last modification date
20/08/2019 16:31
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