Ventral tegmental area subcircuits process rewarding and aversive experiences.

Details

Serval ID
serval:BIB_BD4561E60FF7
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Ventral tegmental area subcircuits process rewarding and aversive experiences.
Journal
Journal of neurochemistry
Author(s)
Bariselli S., Glangetas C., Tzanoulinou S., Bellone C.
ISSN
1471-4159 (Electronic)
ISSN-L
0022-3042
Publication state
Published
Issued date
12/2016
Peer-reviewed
Oui
Volume
139
Number
6
Pages
1071-1080
Language
english
Notes
Publication types: Review ; Journal Article
Publication Status: ppublish
Abstract
The ventral tegmental area is a heterogeneous brain structure that plays a central role in rewarding and aversive experience processing. Studies suggest that several subpopulations within the ventral tegmental area form subcircuits that are differentially involved in rewarding and aversive experiences and that could be individually affected in several neuropsychiatric disorders. Here, we focus on the recent advances concerning the functional description of the three major neuronal subpopulations, in terms of neurotransmitter release, their input and output structures, and their role in controlling specific behavioral outcomes. Several subpopulations within the Ventral Tegmental Area form subcircuits that are differentially involved in rewarding and aversive experiences and that could be individually affected in several neuropsychiatric disorders. We focus on the recent advances concerning the functional description of the three major neuronal subpopulations, their input and output structures, and their role in controlling specific behavioral outcomes. This article is part of a mini review series: "Synaptic Function and Dysfunction in Brain Diseases".

Pubmed
Create date
16/09/2016 17:54
Last modification date
20/08/2019 16:31
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