Fruit and vegetables and cancer risk : a review of southern European studies

Details

Ressource 1Download: serval:BIB_BBC88471D3E6.P001 (249.82 [Ko])
State: Public
Version: author
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_BBC88471D3E6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Fruit and vegetables and cancer risk : a review of southern European studies
Journal
British Journal of Nutrition
Author(s)
Turati F., Rossi M., Pelucchi C., Levi F., La Vecchia C.
ISSN
1475-2662 (Electronic)
ISSN-L
0007-1145
Publication state
Published
Issued date
2015
Volume
113 Suppl 2
Pages
S102-S110
Language
english
Abstract
High intakes of fruit and vegetables may reduce the risk of cancer at several sites. Evidence has been derived mainly from case-control studies. We reviewed the relationship between consumption of vegetables and fruit and the risk of several common cancers in a network of Italian and Swiss case-control studies including over 10 000 cases of fourteen different cancers and about 17 000 controls. Data were suggestive of a protective role of vegetable intake on the risk of several common epithelial cancers. OR for the highest compared with the lowest levels of consumption ranged from 0·2 (larynx, oral cavity and pharynx) to 0·9 (prostate). Inverse associations were found for both raw and cooked vegetables, although for upper digestive tract cancers the former were somewhat stronger. Similar inverse associations were found for cruciferous vegetables. Frequent consumption of allium vegetables was also associated with reduced risk of several cancers. Fruit was a favourable correlate of the risk of several cancers, particularly of the upper digestive tract, with associations generally weaker than those reported for vegetables. A reduced risk of cancers of the digestive tract and larynx was found for high consumption of citrus fruit. Suggestive protections against several forms of cancer, mainly digestive tract cancers, were found for high consumption of apples and tomatoes. High intakes of fibres, flavonoids and proanthocyanidins were inversely related to various forms of cancer. In conclusion, data from our series of case-control studies suggested a favourable role of high intakes of fruit and vegetables in the risk of many common cancers, particularly of the digestive tract. This adds evidence to the indication that aspects of the Mediterranean diet may have a favourable impact not only on CVD, but also on several common (epithelial) cancers, particularly of the digestive tract.
Pubmed
Open Access
Yes
Create date
20/07/2015 10:53
Last modification date
25/09/2019 7:10
Usage data