Free-running 4D whole-heart self-navigated golden angle MRI: Initial results.

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State: Public
Version: author
Serval ID
serval:BIB_BB9E726EB412
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Free-running 4D whole-heart self-navigated golden angle MRI: Initial results.
Journal
Magnetic Resonance In Medicine
Author(s)
Coppo S., Piccini D., Bonanno G., Chaptinel J., Vincenti G., Feliciano H., van Heeswijk R.B., Schwitter J., Stuber M.
ISSN
1522-2594 (Electronic)
ISSN-L
0740-3194
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
74
Number
5
Pages
1306-1316
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
PURPOSE: To test the hypothesis that both coronary anatomy and ventricular function can be assessed simultaneously using a single four-dimensional (4D) acquisition.
METHODS: A free-running 4D whole-heart self-navigated acquisition incorporating a golden angle radial trajectory was implemented and tested in vivo in nine healthy adult human subjects. Coronary magnetic resonance angiography (MRA) datasets with retrospective selection of acquisition window width and position were extracted and quantitatively compared with baseline self-navigated electrocardiography (ECG) -triggered coronary MRA. From the 4D datasets, the left-ventricular end-systolic, end-diastolic volumes (ESV & EDV) and ejection fraction (EF) were computed and compared with values obtained from conventional 2D cine images.
RESULTS: The 4D datasets enabled dynamic assessment of the whole heart with isotropic spatial resolution of 1.15 mm(3). Coronary artery image quality was very similar to that of the ECG-triggered baseline scan despite some SNR penalty. A good agreement between 4D and 2D cine imaging was found for EDV, ESV, and EF.
CONCLUSION: The hypothesis that both coronary anatomy and ventricular function can be assessed simultaneously in vivo has been tested positive. Retrospective and flexible acquisition window selection allows to best visualize each coronary segment at its individual time point of quiescence.
Keywords
Adult, Algorithms, Cardiac Imaging Techniques/methods, Female, Heart/anatomy & histology, Heart/physiology, Humans, Imaging, Three-Dimensional/methods, Magnetic Resonance Imaging/methods, Male, Signal-To-Noise Ratio, Young Adult
Pubmed
Web of science
Create date
12/12/2014 14:34
Last modification date
20/08/2019 15:29
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