The Very Long-Term Outcome of Radiosurgery for Classical Trigeminal Neuralgia.

Details

Serval ID
serval:BIB_BB763DF9AB11
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The Very Long-Term Outcome of Radiosurgery for Classical Trigeminal Neuralgia.
Journal
Stereotactic and Functional Neurosurgery
Author(s)
Régis J., Tuleasca C., Resseguier N., Carron R., Donnet A., Yomo S., Gaudart J., Levivier M.
ISSN
1423-0372 (Electronic)
ISSN-L
1011-6125
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
94
Number
1
Pages
24-32
Language
english
Abstract
BACKGROUND: Radiosurgery is one of the neurosurgical alternatives for intractable trigeminal neuralgia (TN).
OBJECTIVE: Although acceptable short-/mid-term outcomes have been reported, long-term results have not been well documented.
METHODS: We report the long-term results in 130 patients who underwent radiosurgery for classical TN and were subsequently monitored through at least 7 years (median = 9.9, range = 7-14.5) of follow-up.
RESULTS: The median age was 66.5 years. A total of 122 patients (93.8%) became pain free (median delay = 15 days) after the radiosurgery procedure (Barrow Neurological Institute, BNI class I-IIIa). The probability of remaining pain free without medication at 3, 5, 7 and 10 years was 77.9, 73.8, 68 and 51.5%, respectively. Fifty-six patients (45.9%) who were initially pain free experienced recurrent pain (median delay = 73.1 months). However, at 10 years, of the initial 130 patients, 67.7% were free of any recurrence requiring new surgery (BNI class I-IIIa). The new hypesthesia rate was 20.8% (median delay of onset = 12 months), and only 1 patient (0.8%) reported very bothersome hypesthesia.
CONCLUSIONS: The long-term results were comparable to those from our general series (recently published), and the high probability of long-lasting pain relief and rarity of consequential complications of radiosurgery may suggest it as a first- and/or second-line treatment for classical, drug-resistant TN.
Pubmed
Web of science
Open Access
Yes
Create date
10/05/2016 14:28
Last modification date
20/08/2019 16:29
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