Challenges to curing primary brain tumours.

Details

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State: Public
Version: author
License: CC BY 4.0
Serval ID
serval:BIB_BAF957625821
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Challenges to curing primary brain tumours.
Journal
Nature reviews. Clinical oncology
Author(s)
Aldape K., Brindle K.M., Chesler L., Chopra R., Gajjar A., Gilbert M.R., Gottardo N., Gutmann D.H., Hargrave D., Holland E.C., Jones DTW, Joyce J.A., Kearns P., Kieran M.W., Mellinghoff I.K., Merchant M., Pfister S.M., Pollard S.M., Ramaswamy V., Rich J.N., Robinson G.W., Rowitch D.H., Sampson J.H., Taylor M.D., Workman P., Gilbertson R.J.
ISSN
1759-4782 (Electronic)
ISSN-L
1759-4774
Publication state
Published
Issued date
08/2019
Peer-reviewed
Oui
Volume
16
Number
8
Pages
509-520
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Abstract
Despite decades of research, brain tumours remain among the deadliest of all forms of cancer. The ability of these tumours to resist almost all conventional and novel treatments relates, in part, to the unique cell-intrinsic and microenvironmental properties of neural tissues. In an attempt to encourage progress in our understanding and ability to successfully treat patients with brain tumours, Cancer Research UK convened an international panel of clinicians and laboratory-based scientists to identify challenges that must be overcome if we are to cure all patients with a brain tumour. The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment.
Keywords
Brain Neoplasms/therapy, Humans
Pubmed
Web of science
Open Access
Yes
Create date
25/03/2019 10:30
Last modification date
28/01/2020 6:20
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