Diagnostic des retards pubertaires [Diagnosis of delayed puberty]

Details

Serval ID
serval:BIB_BADCCFB6E93F
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Diagnostic des retards pubertaires [Diagnosis of delayed puberty]
Journal
Archives de pediatrie
Author(s)
Busiah K., Belien V., Dallot N., Fila M., Guilbert J., Harroche A., Leger J.
ISSN
0929-693X (Print)
ISSN-L
0929-693X
Publication state
Published
Issued date
09/2007
Peer-reviewed
Oui
Volume
14
Number
9
Pages
1101-1110
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Abstract
Puberty is the phenomenon that conducts once to reproductive maturation. Delayed puberty (DP) is defined by the absence of testicular development in boys beyond 14 years old (or a testicular volume lower than 4 ml) and by the absence of breast development in girls beyond 13 years old. DP occurs in approximatively 3% of cases. Most cases are functional DP, with a large amount of constitutional delay of puberty. Others etiologies are hypogonadotrophic hypogonadism like Kallmann syndrome, or hypergonadotrophic hypogonadism. Turner syndrome is a diagnostic one should not forget by its frequency. Treatment is hormonal replacement therapy and of the etiology. During the last decade, many genes have been identified and elucidated the etiological diagnosis of some hypogonadotrophic hypogonadism syndrome. Further studies are required in collaboration with molecular biologists to better understand the mechanism of hypothalamic pituitary gonadal axis abnormalities and of the neuroendocrine physiology of the onset of puberty.
Keywords
Androgens/therapeutic use, Estradiol/therapeutic use, Female, Hormone Replacement Therapy, Humans, Hypogonadism/complications, Male, Puberty/physiology, Puberty, Delayed/diagnosis, Puberty, Delayed/drug therapy, Puberty, Delayed/etiology, Testosterone/therapeutic use, Turner Syndrome/complications
Pubmed
Web of science
Create date
30/03/2020 14:50
Last modification date
31/03/2020 5:26
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