Fluorescence cystoscopy in the management of bladder cancer: a help for the urologist!

Details

Serval ID
serval:BIB_BABC56CCF93A
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Fluorescence cystoscopy in the management of bladder cancer: a help for the urologist!
Journal
Urologia Internationalis
Author(s)
Jichlinski  P., Leisinger  H. J.
ISSN
0042-1138
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
74
Number
2
Pages
97-101
Notes
Journal Article
Review
Abstract
As a disease characterized by a nature polymorphic and fluctuant in its evolution, superficial transitional cell carcinoma of the bladder remains a perpetual therapeutic challenge, and raises a great interest in the development of new diagnostic and surveillance techniques. This paper reviews 10 years of experience of fluorescence cystoscopy, a simple technique perfectly adapted to the current endoscopic equipment. Its principle is to enhance the visual contrast between benign and malignant cells. Three photosensitizing agents are available, two prodrugs: delta-aminolevulinic acid or hexaminolevulinate, and a natural substance: hypericin. With a detection rate of over 90% for carcinoma in situ and a real potential for detecting small tumors overlooked by standard cystoscopy, fluorescence cystoscopy may be clearly recommended in clinical practice. This technique favors a standardization of superficial bladder cancer endoscopic management and is susceptible to have a real impact on the disease recurrence and progression rate.
Keywords
Cystoscopy/*methods Fluorescence Humans Urinary Bladder Neoplasms/*diagnosis Urology/methods
Pubmed
Web of science
Create date
21/01/2008 16:09
Last modification date
20/08/2019 15:28
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