Nabothian cyst content: A potential pitfall for the diagnosis of invasive cancer on Pap test cytology.

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Version: Author's accepted manuscript
Serval ID
serval:BIB_BAB901D03B65
Type
Article: article from journal or magazin.
Collection
Publications
Title
Nabothian cyst content: A potential pitfall for the diagnosis of invasive cancer on Pap test cytology.
Journal
Diagnostic cytopathology
Author(s)
Barrigón A., Ziadi S., Jacot-Guillarmod M., Da Silva S., Dumont M., Raineri I., Bongiovanni M.
ISSN
1097-0339 (Electronic)
ISSN-L
1097-0339
Publication state
Published
Issued date
02/2019
Peer-reviewed
Oui
Volume
47
Number
2
Pages
127-129
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Abstract
Nabothian cysts are common, benign findings of the squamocolumnar junction of the adult cervix. These cysts are filled with mucus and can also contain proteinaceous material, neutrophils, or neutrophil debris. Nabothian cysts can be broken by the spatula during smear taking, may stick to the brush and be smeared onto slides in conventional cytology or dissolved in the preserving solution for liquid-based cytology (LBC) preparations. The granular content of Nabothian cysts may be mistaken for the tumor diathesis (TD) pattern associated with invasive carcinoma. In the case described, the patient presented a high-grade squamous intraepithelial lesion associated with granular material (Nabothian cyst content) that we considered erroneously on LBC to be TD-like material, thus, raising the suspicion of invasive carcinoma. To the best of our knowledge, this is the first report showing that Nabothian cyst content may present a potential pitfall in the diagnosis of invasive carcinoma on LBC.
Keywords
Adult, Cervical Intraepithelial Neoplasia/diagnosis, Cervical Intraepithelial Neoplasia/pathology, Cysts/pathology, Diagnosis, Differential, Female, Humans, Papanicolaou Test, Precancerous Conditions/diagnosis, Precancerous Conditions/pathology, Uterine Cervical Neoplasms/diagnosis, Uterine Cervical Neoplasms/pathology, Vaginal Smears/methods, Nabothian cyst, cervical cancer, liquid-based cytology, tumor diathesis
Pubmed
Web of science
Create date
02/11/2018 9:52
Last modification date
20/08/2019 16:28
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