Physical activity and energy expenditure in rheumatoid arthritis patients and matched controls.

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State: Public
Version: author
Serval ID
serval:BIB_BAAD5D13D4E3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Physical activity and energy expenditure in rheumatoid arthritis patients and matched controls.
Journal
Rheumatology
Author(s)
Henchoz Y., Bastardot F., Guessous I., Theler J.M., Dudler J., Vollenweider P., So A.
ISSN
1462-0332 (Electronic)
ISSN-L
1462-0324
Publication state
Published
Issued date
2012
Volume
51
Number
8
Pages
1500-1507
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish
Abstract
OBJECTIVES: To compare daily energy expenditure between RA patients and matched controls, and to explore the relationship between daily energy expenditure or sedentariness and disease-related scores.
METHODS: One hundred and ten patients with RA and 440 age- and sex-matched controls were included in this study. Energy expenditure was assessed using the validated physical activity (PA) frequency questionnaire. Disease-related scores included disease activity (DAS-28), functional status (HAQ), pain visual analogue scale (VAS) and fatigue VAS. Total energy expenditure (TEE) and the amount of energy spent in low- (TEE-low), moderate- (TEE-mod) and high-intensity (TEE-high) PAs were calculated. Sedentariness was defined as expending <10% of TEE in TEE-mod or TEE-high activities. Between-group comparisons were computed using conditional logistic regression. The effect of disease-related scores on TEE was investigated using linear regression.
RESULTS: TEE was significantly lower for RA patients compared with controls [2392 kcal/day (95% CI 2295, 2490) and 2494  kcal/day (2446, 2543), respectively, P = 0.003]. A significant difference was found between groups in TEE-mod (P = 0.015), but not TEE-low (P = 0.242) and TEE-high (P = 0.146). All disease-related scores were significantly poorer in sedentary compared with active patients. TEE was inversely associated with age (P < 0.001), DAS-28 (P = 0.032) and fatigue VAS (P = 0.029), but not with HAQ and pain VAS.
CONCLUSION: Daily energy expenditure is significantly lower in RA patients compared with matched controls, mainly due to less moderate-intensity PAs performed. Disease activity and fatigue are important contributing factors. These points need to be addressed if promoting PA in RA patients is a health goal. Trial registration. ClinicalTrials.gov, http://clinicaltrials.gov, NCT01228812.
Keywords
Adult, Age Factors, Aged, Aged, 80 and over, Arthritis, Rheumatoid/complications, Arthritis, Rheumatoid/physiopathology, Body Mass Index, Case-Control Studies, Cross-Sectional Studies, Energy Metabolism/physiology, Exercise/physiology, Fatigue/etiology, Female, Humans, Linear Models, Male, Middle Aged, Pain Measurement, Questionnaires, Sedentary Lifestyle, Severity of Illness Index
Pubmed
Web of science
Open Access
Yes
Create date
27/08/2012 18:11
Last modification date
20/08/2019 16:28
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