Allergic bronchopulmonary aspergillosis: the hunt for a diagnostic serological marker in cystic fibrosis patients.

Details

Serval ID
serval:BIB_BA5159FEA0EB
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Allergic bronchopulmonary aspergillosis: the hunt for a diagnostic serological marker in cystic fibrosis patients.
Journal
Expert Review of Molecular Diagnostics
Author(s)
Hafen G.M., Hartl D., Regamey N., Casaulta C., Latzin P.
ISSN
1744-8352[electronic]
Publication state
Published
Issued date
2009
Volume
9
Number
2
Pages
157-164
Language
english
Abstract
The diagnosis of allergic bronchopulmonary aspergillosis (ABPA) in cystic fibrosis patients remains challenging, mainly owing to overlapping symptoms of the underlying lung disease with clinical symptoms of ABPA. In addition, a varying mixture of diagnostic criteria, including clinical status, radiological findings and immunological measurements, has led to confusion and differing recommendations. In order to help simplify as well as standardize the diagnostic criteria for ABPA, different serological markers have been evaluated in the last 20 years and their usefulness has been assessed in many clinical studies. This review presents current diagnostic criteria of ABPA, with a special focus on serum markers supporting the diagnosis and explains why the hunt for a serological marker for ABPA is still ongoing.
Keywords
Aspergillosis, Allergic Bronchopulmonary/blood, Aspergillosis, Allergic Bronchopulmonary/diagnosis, Biological Markers/blood, Cystic Fibrosis/blood, Cystic Fibrosis/complications, Diagnosis, Differential, Humans
Pubmed
Web of science
Create date
27/06/2009 14:13
Last modification date
20/08/2019 15:28
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