How single-trial electrical neuroimaging contributes to multisensory research.

Details

Serval ID
serval:BIB_B8CBABF898D3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
How single-trial electrical neuroimaging contributes to multisensory research.
Journal
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale
Author(s)
Gonzalez Andino S.L., Murray M.M., Foxe J.J., de Peralta Menendez R.G.
ISSN
0014-4819
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
166
Number
3-4
Pages
298-304
Language
english
Notes
Publication types: Clinical Trial ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Abstract
This study details a method to statistically determine, on a millisecond scale and for individual subjects, those brain areas whose activity differs between experimental conditions, using single-trial scalp-recorded EEG data. To do this, we non-invasively estimated local field potentials (LFPs) using the ELECTRA distributed inverse solution and applied non-parametric statistical tests at each brain voxel and for each time point. This yields a spatio-temporal activation pattern of differential brain responses. The method is illustrated here in the analysis of auditory-somatosensory (AS) multisensory interactions in four subjects. Differential multisensory responses were temporally and spatially consistent across individuals, with onset at approximately 50 ms and superposition within areas of the posterior superior temporal cortex that have traditionally been considered auditory in their function. The close agreement of these results with previous investigations of AS multisensory interactions suggests that the present approach constitutes a reliable method for studying multisensory processing with the temporal and spatial resolution required to elucidate several existing questions in this field. In particular, the present analyses permit a more direct comparison between human and animal studies of multisensory interactions and can be extended to examine correlation between electrophysiological phenomena and behavior.
Keywords
Acoustic Stimulation, Adult, Brain, Brain Mapping, Diagnostic Imaging, Electroencephalography, Electrophysiology, Evoked Potentials, Evoked Potentials, Somatosensory, Female, Humans, Linear Models, Male, Mental Processes, Research Design
Pubmed
Web of science
Create date
21/01/2008 10:23
Last modification date
20/08/2019 15:26
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