Dpp/BMP signaling in flies: From molecules to biology.

Details

Serval ID
serval:BIB_B84894D47D41
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Dpp/BMP signaling in flies: From molecules to biology.
Journal
Seminars in Cell and Developmental Biology
Author(s)
Hamaratoglu F., Affolter M., Pyrowolakis G.
ISSN
1096-3634 (Electronic)
ISSN-L
1084-9521
Publication state
Published
Issued date
2014
Volume
32C
Pages
128-136
Language
english
Abstract
Decapentaplegic (Dpp), the fly homolog of the secreted mammalian BMP2/4 signaling molecules, is involved in almost all aspects of fly development. Dpp has critical functions at all developmental stages, from patterning of the eggshell to the determination of adult intestinal stem cell identity. Here, we focus on recent findings regarding the transcriptional regulatory logic of the pathway, on a new feedback regulator, Pentagone, and on Dpp's roles in scaling and growth of the Drosophila wing.
Keywords
Drosophila, Dpp, Morphogen, Scaling, Growth, Patterning, Feedback regulation, Pentagone, Brinker, Spalt, Optomotor blind, Daughters-against-dpp, Dally, Silencer Element, Activating Element
Pubmed
Web of science
Open Access
Yes
Create date
04/09/2014 8:34
Last modification date
20/08/2019 15:26
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