Benign biliary inflammatory pseudotumor mimicking a Klatskin tumor.

Details

Serval ID
serval:BIB_B807D14B7FC1
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Benign biliary inflammatory pseudotumor mimicking a Klatskin tumor.
Journal
Hepato-gastroenterology
Author(s)
Gohy S., Hubert C., Deprez P., Van Beers B.E., Annet L., Lhommel R., Sempoux C., Jean-François G.
ISSN
0172-6390 (Print)
ISSN-L
0172-6390
Publication state
Published
Issued date
2007
Peer-reviewed
Oui
Volume
54
Number
77
Pages
1348-1352
Language
english
Notes
Publication types: Case Reports ; Journal Article Publication Status: ppublish
Abstract
Most biliary tumors at the liver hilum are malignant and, when possible, require radical surgical resection. However, few rare benign lesions exist, for which the differential diagnosis with malignancy is important in order to avoid aggressive surgical treatment. This is a retrospective case report. We report on two patients suffering from presumed inflammatory pseudotumor of the main biliary convergence, mimicking a Klatskin's tumor. Complete multidisciplinary work-up in a specialized hepatobiliary centre, including tumor markers, imaging studies and FDG-PET were strongly in favor of malignancy. The benign nature of the lesions was only suspected on the natural radiological evolution during the time waiting for surgical resection, with progressive spontaneous disappearance of tumor masses. Therefore, we were able to avoid extensive hepatobiliary surgery in both patients, including performance of an extended right hepatectomy. However, the patients had portal vein embolization as a first step in treating the disease, hopefully with no long-term consequences on patient status and liver function tests. Clinicians should be aware that tumors arising at the hepatic bifurcation are not always malignant, even if it is the most frequent cause. Despite extensive multidisciplinary work-up, there are still persisting difficulties in this differential diagnosis.
Keywords
Adult, Bile Duct Diseases/diagnosis, Bile Duct Neoplasms/diagnosis, Diagnosis, Differential, Female, Granuloma, Plasma Cell/diagnosis, Hepatic Duct, Common, Humans, Klatskin Tumor/diagnosis, Middle Aged, Retrospective Studies
Pubmed
Web of science
Create date
20/10/2016 16:09
Last modification date
20/08/2019 15:26
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