Life-threatening hemorrhagic diathesis due to disseminated intravascular coagulation during elective brain tumor surgery

Details

Serval ID
serval:BIB_B7CA677D3863
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Life-threatening hemorrhagic diathesis due to disseminated intravascular coagulation during elective brain tumor surgery
Journal
Journal of Neurosurgical Anesthesiology
Author(s)
Berger  M. M., Ravussin  P., Vielle  G., Fankhauser  H.
ISSN
0898-4921
Publication state
Published
Issued date
01/1995
Peer-reviewed
Oui
Volume
7
Number
1
Pages
26-9
Notes
Case Reports
Journal Article --- Old month value: Jan
Abstract
Disseminated intravascular coagulation (DIC) is an extremely rare complication during elective brain tumor surgery. We report the case of a life-threatening intraoperative hemorrhagic diathesis due to a fulminating DIC during the removal of a grade III parietooccipital astrocytoma in a patient with a history of three pulmonary embolisms. Intraoperatively, the patient required 13 U of blood, 9 U of fresh-frozen plasma, and 5.45 L of colloids and crystalloids (total volume infused during the procedure: 12.5 L). Bleeding persisted for 24 h and required further blood component therapy. Laboratory data support the diagnosis of DIC: decreased fibrinogen and platelet count, prolonged thrombin and prothrombin times, and the presence of fibrin monomers. With aggressive and swift treatment of the DIC, the patient survived with transient neurological worsening.
Keywords
Blood Component Transfusion Blood Loss, Surgical Blood Transfusion Brain Neoplasms/*surgery Colloids/therapeutic use Disseminated Intravascular Coagulation/*etiology Glioblastoma/*surgery Humans *Intraoperative Complications Isotonic Solutions Male Middle Aged Plasma Substitutes/therapeutic use Rehydration Solutions/therapeutic use Surgical Procedures, Elective
Pubmed
Web of science
Create date
21/01/2008 17:30
Last modification date
20/08/2019 15:25
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