Reduced active thyroid hormone levels in acute illness

Details

Serval ID
serval:BIB_B777961B9B06
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Reduced active thyroid hormone levels in acute illness
Journal
Lancet
Author(s)
Burger  A., Nicod  P., Suter  P., Vallotton  M. B., Vagenakis  P., Braverman  L.
ISSN
0140-6736 (Print)
Publication state
Published
Issued date
03/1976
Volume
1
Number
7961
Pages
653-5
Notes
Journal Article --- Old month value: Mar 27
Abstract
In acute and subacute disease the active thyroid hormones, triiodothyronine (T3) and tetraiodothyroacetic acid (tetrac), are decreased while serum-thyroxine (T4) levels tend to be slightly reduced. Conversely, the inactive metabolite, reverse triiodothyronine (reverse T3), is increased indicating a diversion of T4 metabolism from an activating to an inactivating pathway. With convalescence the serum levels of T3, tetrac, and T4 recover while reverse T3 decreases to normal. These changes occur without significant alterations in serum levels of thyroid-stimulating hormone, indicating maintenance of euthyroidism throughout disease.
Keywords
*Acute Disease Adult Aged Bronchitis/blood Cardiovascular Diseases/blood Child Female Gastroenteritis/blood Humans Infectious Mononucleosis/blood Lung Diseases/blood Male Middle Aged Q Fever/blood Salmonella Infections/blood Thyroid Hormones/*blood Thyroxine/analogs & derivatives/blood Triiodothyronine/blood
Pubmed
Web of science
Create date
25/01/2008 14:59
Last modification date
20/08/2019 16:25
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