Ultrasound measurements on the os calcis in a prospective multicenter study.

Details

Serval ID
serval:BIB_B76D105BA88B
Type
Article: article from journal or magazin.
Collection
Publications
Title
Ultrasound measurements on the os calcis in a prospective multicenter study.
Journal
Calcified Tissue International
Author(s)
Hans D., Schott A.M., Chapuy M.C., Benamar M., Kotzki P.D., Cormier C., Pouilles J.M., Meunier P.J.
ISSN
0171-967X
Publication state
Published
Issued date
1994
Peer-reviewed
Oui
Volume
55
Number
2
Pages
94-99
Language
english
Abstract
Ultrasonic assessment is a new approach to assess both quality and density. Two ultrasonic parameters are measured on the os calcis: the attenuation or broadband ultrasound attenuation (BUA) and the velocity or speed of sound (SOS). The interunit variations in vitro and in vivo of an ultrasound instrument, the Lunar Achilles system, used in a French multicenter study named EPIDOS, were calculated and the stability of these instruments over a 12-month period was evaluated. A third parameter called "stiffness index," calculated from the SOS and BUA, was also used in this study. The average CV in vitro for the BUA and SOS was 0.92% and 0.12%, respectively, and the average CV in vivo for the BUA, the SOS, and the stiffness index was 1.83%, 0.23%, and 1.9%, respectively. The interunit (or inter-machines) variations were calculated by a one-way analysis of variance. We detected small but significant measurement differences among centers on a phantom for both SOS (maximum significant difference 0.4%) and stiffness (maximum significant difference 3.5%) but not for BUA. Similar differences were found in vivo. The precision over 12 months of the interunit variations in vitro was evaluated by measuring a single phantom traveling from one center to another several times. The range of the CV for the BUA (1.54-0.51%), for the SOS (0.25-0.14%), and for the stiffness index (2.26-1.10%) are explained in part by technical failures. The variation among the five Achilles was estimated by the combined CV which was 1.42% for the BUA, 0.32% for the SOS, and 2.33% for the stiffness index. In conclusion, our findings indicate that equipment from one manufacturer appears to be consistent between machines for the BUA, but not completely for the SOS. The results for this stiffness index are necessarily influenced by both SOS and BUA. The short-term and long-term interunit precision is good, both in vitro and in vivo. Such results provide increased confidence in multicenter clinical trials where ultrasonic data are pooled.
Keywords
Adult, Aged, Analysis of Variance, Bone Density, Calcaneus, Female, Humans, Male, Middle Aged, Prospective Studies, Quality Control, Ultrasonography
Pubmed
Web of science
Create date
02/03/2009 12:33
Last modification date
20/08/2019 15:25
Usage data