Incidence of childhood renal tumours: An international population-based study.
Details
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_B6E4CCC95FE0
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Incidence of childhood renal tumours: An international population-based study.
Journal
International journal of cancer
Working group(s)
IICC-3 Contributors
Contributor(s)
Bulliard J.L.
ISSN
1097-0215 (Electronic)
ISSN-L
0020-7136
Publication state
Published
Issued date
15/12/2020
Peer-reviewed
Oui
Volume
147
Number
12
Pages
3313-3327
Language
english
Notes
Publication types: Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
Malignant renal tumours represent 5% of childhood cancers and include types with likely different aetiology: Wilms tumour (WT), rhabdoid renal tumour, kidney sarcomas and renal carcinomas. WT is the most common renal tumour in children, previously shown to vary internationally and with ethnicity. Using the comprehensive database of the International Incidence of Childhood Cancer study (IICC), we analysed global variations and time trends in incidence of renal tumour types in children (age 0-14 years) and adolescents (age 15-19 years). The results were presented by 14 world regions, and five ethnic groups in the US. We included 15 320 renal tumours in children and 800 in adolescents reported to the 163 contributing registries during 2001-2010. In children, age-standardised incidence rate (ASR) of renal tumours was 8.3 per million (95% confidence interval, CI = 8.1, 8.4); it was the highest in North America and Europe (9-10 per million) and the lowest in most Asian regions (4-5 per million). In the US, Blacks had the highest ASR (10.9 per million, 95% CI = 10.2, 11.6) and Asian and Pacific Islanders the lowest (4.4 per million, 95% CI = 3.6, 5.1). In adolescents, age-specific incidence rate of renal tumours was 1.4 per million (95% CI = 1.3, 1.5). WT accounted for over 90% of all renal tumours in each age from 1 to 7 years and the proportion of renal carcinomas increased gradually with age. From 1996 to 2010, incidence remained mostly stable for WT (average annual percent change, AAPC = 0.1) and increased for renal carcinomas in children (AAPC = 3.7) and adolescents (AAPC = 3.2). Our findings warrant further monitoring.
Keywords
Adolescent, Child, Child, Preschool, Female, Global Health/ethnology, Humans, Incidence, Infant, Infant, Newborn, Kidney Neoplasms/epidemiology, Male, Registries, Rhabdoid Tumor/epidemiology, Sarcoma/epidemiology, Wilms Tumor/epidemiology, Wilms tumour, cancer epidemiology, childhood renal tumour, paediatric kidney cancer, population-based cancer registry study
Pubmed
Web of science
Open Access
Yes
Create date
15/06/2023 11:07
Last modification date
25/01/2024 8:43