Frontal cortical thickness correlates positively with impulsivity in early psychosis male patients.

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Version: Author's accepted manuscript
License: Not specified
Serval ID
serval:BIB_B65A2239B3B8
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Frontal cortical thickness correlates positively with impulsivity in early psychosis male patients.
Journal
Early intervention in psychiatry
Author(s)
Baumann P.S., Klauser P., Griffa A., Golay P., Palix J., Alameda L., Moulin V., Hagmann P., Do K.Q., Conus P.
ISSN
1751-7893 (Electronic)
ISSN-L
1751-7885
Publication state
Published
Issued date
08/2019
Peer-reviewed
Oui
Volume
13
Number
4
Pages
848-852
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Impulsive behaviours, which are frequent in young people suffering from psychosis have been linked to risky and violent behaviours and participate to the burden of psychotic illness. Given that morphological brain correlates of impulsivity in schizophrenia have been poorly investigated especially in young adults, the aim of this study was to investigate the relationship between impulsivity and cortical thickness in early psychosis (EP) patients.
A total of 17 male subjects in the early phase of psychosis were recruited. Impulsivity was assessed with the Lecrubier Impulsivity Rating Scale. Mean cortical thickness was extracted from magnetic resonance imaging brain scans, using surface-based methods.
Mean cortical thickness in the frontal lobe correlated positively with mean impulsivity in EP male patients.
Our results suggest that psychotic subjects exhibiting higher impulsivity have larger frontal cortical thickness, which may pave the way towards the identification of patients with a higher risk to display impulsive behaviours.
Keywords
cortical thickness, early psychosis, impulsivity, magnetic resonance imaging, violence
Pubmed
Web of science
Create date
14/03/2018 12:23
Last modification date
21/04/2020 5:19
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