Characteristics of aldosterone antisera related to the duration of immunization

Details

Serval ID
serval:BIB_B60264BCA1C8
Type
Article: article from journal or magazin.
Collection
Publications
Title
Characteristics of aldosterone antisera related to the duration of immunization
Journal
Hormone Research
Author(s)
Schmied  U., Siegenthaler  W., Nussberger  J., Beckerhoff  R., Vetter  W.
ISSN
0301-0163 (Print)
Publication state
Published
Issued date
1976
Volume
7
Number
1
Pages
28-33
Notes
Journal Article
Abstract
Three antisera specific to aldosterone and elicited with different aldosterone protein conjugates (aldosterone-3-oxine rabbit serum albumin and aldosterone-3-oxime bovine gamma-globulin) were studied by radioimmunological methods at various times subsequent to first-immunization. A considerable variability of the parameters important in radioimmunoassay was observed over the whole experimental period. Titer, sensitivity and specificity of two antisera tended to increase as long as the animals were boosted. In the third they did not change in a uniform way.
Keywords
Aldosterone/*immunology Animals Antibodies Cross Reactions Dose-Response Relationship, Drug *Immune Sera *Immunization Male Microchemistry Oximes Rabbits/immunology Time Factors
Pubmed
Web of science
Create date
05/03/2008 16:41
Last modification date
20/08/2019 15:24
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