Clinical research in palliative care: choice of trial design

Details

Serval ID
serval:BIB_B58E862ADEDE
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Clinical research in palliative care: choice of trial design
Journal
Palliative Medicine
Author(s)
Mazzocato  C., Sweeney  C., Bruera  E.
ISSN
0269-2163 (Print)
Publication state
Published
Issued date
05/2001
Volume
15
Number
3
Pages
261-4
Notes
Journal Article --- Old month value: May
Abstract
Prospective controlled clinical trials provide the highest level of evidence in palliative care. Both parallel and crossover studies have unique advantages and disadvantages. Excellent knowledge of the patient population, interventions and endpoints are useful in choosing the most appropriate trial. Open pilot studies can assist the investigator in understanding the intervention and measurement tools better before embarking in costly and lengthy controlled trials. More controlled clinical trails are need to generate the evidence that will advance patient management in palliative care.
Keywords
Cross-Over Studies Double-Blind Method Humans *Palliative Care Pilot Projects *Randomized Controlled Trials *Research Design Statistics, Nonparametric
Pubmed
Web of science
Create date
24/01/2008 16:37
Last modification date
20/08/2019 15:24
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