Hydroxyurea with continuous infusion paclitaxel, 5-fluorouracil, and concomitant radiotherapy for poor-prognosis head and neck cancer

Details

Serval ID
serval:BIB_B51990F50C8F
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Hydroxyurea with continuous infusion paclitaxel, 5-fluorouracil, and concomitant radiotherapy for poor-prognosis head and neck cancer
Journal
Seminars in Oncology
Author(s)
Vokes  E. E., Stupp  R., Haraf  D., Moran  W., Malone  D., Wenig  B., Sweeney  P., Weichselbaum  R. R.
ISSN
0093-7754 (Print)
Publication state
Published
Issued date
06/1995
Volume
22
Number
3 Suppl 6
Pages
47-52
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review --- Old month value: Jun
Abstract
Concomitant chemoradiotherapy holds promise in the therapy of advanced head and neck cancer. We have previously reported on the combination of 5-fluorouracil, hydroxyurea, and concomitant chemoradiotherapy administered on an alternate-week basis. In this ongoing study, we are testing the feasibility of adding continuous-infusion paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) to this combination. Background information and early clinical data are presented.
Keywords
Antineoplastic Combined Chemotherapy Protocols/administration & dosage/*therapeutic use Clinical Trials Combined Modality Therapy Fluorouracil/administration & dosage Head and Neck Neoplasms/*drug therapy/*radiotherapy Humans Hydroxyurea/administration & dosage Infusions, Intravenous Paclitaxel/administration & dosage
Pubmed
Web of science
Create date
28/01/2008 9:39
Last modification date
20/08/2019 16:23
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