Vertebral fracture assessment, trabecular bone score and handgrip in a group of postmenopausal women with vertebral fractures - preliminary study.

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Serval ID
serval:BIB_B503F85E8516
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Vertebral fracture assessment, trabecular bone score and handgrip in a group of postmenopausal women with vertebral fractures - preliminary study.
Journal
Reumatologia
Author(s)
Amarowicz J., Czerwiński E., Kumorek A., Warzecha M., Berwecka M., Hans D.
ISSN
0034-6233 (Print)
ISSN-L
0034-6233
Publication state
Published
Issued date
2018
Peer-reviewed
Oui
Volume
56
Number
2
Pages
80-86
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
The aim of our study was to determine a possible correlation between vertebral fractures (indicated by VFA - vertebral fracture assessment), TBS (trabecular bone score) and muscle strength (measured by means of handgrip strength test results) in a group of postmenopausal women.
The study was conducted between 2014 and 2015 in a group of patients of Krakow Medical Centre (KMC). Women who participated in the study were referred to KMC by an attending physician for suspected vertebral fracture. Apart from VFA, patients were additionally tested for bone density (including TBS), muscle strength (by means of a handgrip strength test) and height loss. Altogether 35 patients with an average age of 69.7 years (49-95, SD = 10.49) were included in the study.
In the group of 35 women, VFA analysis demonstrated vertebral fractures in 17 patients (40%). Vertebral height loss suggesting a fracture was revealed in 77 vertebrae. The mean result of the TBS was 1.195 (0.982-1.409, SD = 0.09), which suggests high risk of fracture. The majority of the subjects (65.7%) displayed major bone microarchitecture degradation (TBS < 1.23) and also the highest number of fractures ( <i>n</i> = 62, 80.5% of all). There was no correlation between the spine bone mineral density (BMD) score and the TBS result, which confirms studies showing that subjects with the same bone density may have completely different TBS. Bone density (spine BMD) was similar (osteopenic) in groups with or without vertebral fracture (in VFA). We noted a significant correlation ( <i>r</i> = 0.45, <i>p</i> < 0.05) between the number of fractured vertebrae and the handgrip score.
VFA should be a part of a standard diagnostic procedure for patients with osteoporotic fractures. When it comes to identifying patients at risk of fracturing vertebrae, muscle strength (handgrip) may have potential use in clinical practice. The predictive value of the TBS in reference to vertebral fractures should be evaluated in bigger randomized studies.
Keywords
handgrip, trabecular bone score, vertebral fracture, vertebral fracture assessment
Pubmed
Open Access
Yes
Create date
15/06/2018 17:09
Last modification date
20/08/2019 15:23
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