Gonadotrophin response to LH-RH in boys with delayed growth and adolescence
Details
Serval ID
serval:BIB_B3853B7D9A9F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Gonadotrophin response to LH-RH in boys with delayed growth and adolescence
Journal
Archives of Disease in Childhood
ISSN
1468-2044 (Electronic)
Publication state
Published
Issued date
07/1981
Volume
56
Number
7
Pages
552-6
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jul
Research Support, Non-U.S. Gov't --- Old month value: Jul
Abstract
Plasma luteinising hormone (LH) and follicle-stimulating hormone (FSH) concentrations were measured before and after intravenous luteinising hormone-releasing hormone (LH-RH) in 33 boys with growth delay. Eighteen were prepubertal and 15 pubertal. Basal LH and FSH levels were low in both groups with mean increments after LH-RH of 3.2 +/- 0.8 U/l (mean +/- SEM) and 2.6 +/- 0.4 U/l respectively in the prepubertal and 7.4 +/- 0.7 U/l and 2.0 +/- 0.3 U/l in the pubertal boys. The LH increment showed a positive correlation with increasing bone age (r = 0.71, P less than 0.001); FSH did not. The LH-RH response thus appeared normal in relation to the stage of maturity.
Keywords
Adolescent
Age Determination by Skeleton
Body Height
Child
Dose-Response Relationship, Drug
Follicle Stimulating Hormone/*blood
Gonadotropin-Releasing Hormone/*diagnostic use
Growth Disorders/*blood
Humans
Luteinizing Hormone/*blood
Male
Pituitary Function Tests
Puberty
Puberty, Delayed/blood
Pubmed
Web of science
Open Access
Yes
Create date
25/01/2008 11:30
Last modification date
20/08/2019 16:22