Role of Antifungal Susceptibility Testing in Non-Aspergillus Invasive Mold Infections.

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Serval ID
serval:BIB_B31E04F5779C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
UNIL/CHUV
Title
Role of Antifungal Susceptibility Testing in Non-Aspergillus Invasive Mold Infections.
Journal
Journal of clinical microbiology
Author(s)
Lamoth F., Damonti L., Alexander B.D.
ISSN
1098-660X (Electronic)
ISSN-L
0095-1137
Publication state
Published
Issued date
06/2016
Peer-reviewed
Oui
Volume
54
Number
6
Pages
1638-1640
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
No clinical breakpoints are available to delineate antifungal drug efficacy in non-Aspergillus invasive mold infections (NAIMIs). In this analysis of 39 NAIMI episodes, the MIC of the first-line antifungal drug was the most important predictor of therapeutic response. For amphotericin B, an MIC of ≤0.5 μg/ml was significantly associated with better 6-week outcomes.
Keywords
Adolescent, Adult, Aged, Amphotericin B/pharmacology, Amphotericin B/therapeutic use, Antifungal Agents/pharmacology, Antifungal Agents/therapeutic use, Child, Child, Preschool, Fungi/drug effects, Humans, Invasive Fungal Infections/drug therapy, Invasive Fungal Infections/microbiology, Male, Microbial Sensitivity Tests, Middle Aged, Prognosis, Retrospective Studies, Treatment Outcome, Young Adult
OAI-PMH
oai:serval.unil.ch:BIB_B31E04F5779C
DOI
10.1128/JCM.00318-16
Pubmed
27008871
Web of science
000376529200034
Open Access
Yes
Create date
03/10/2019 7:38
Last modification date
04/10/2019 5:26
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