Transpupillary thermotherapy of juxtafoveal recurrent choroidal neovascularization.

Details

Serval ID
serval:BIB_B30B161F10AF
Type
Article: article from journal or magazin.
Collection
Publications
Title
Transpupillary thermotherapy of juxtafoveal recurrent choroidal neovascularization.
Journal
European journal of ophthalmology
Author(s)
Cardillo Piccolino F., Eandi C.M., Ventre L., Rigault De La Longrais R.C., Grignolo F.M.
ISSN
1120-6721 (Print)
ISSN-L
1120-6721
Publication state
Published
Issued date
06/2003
Peer-reviewed
Oui
Volume
13
Number
5
Pages
453-460
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
To evaluate the effectiveness of low power transpupillary thermotherapy (TTT) in treating juxtafoveal recurrent choroidal neovascularization (CNV) after laser photocoagulation in patients with age-related macular degeneration (ARMD).
Eight eyes of eight patients with ARMD and juxtafoveal recurrent CNV were treated with low power TTT, delivered using an 810-nm diode laser with 350 mW, 2.0 mm spot, and 1-minute duration. Visual acuity (VA) ranged from 20/100 to 20/50. Treatment effect was evaluated by fluorescein angiography, indocyanine green angiography, and VA measurements (Early Treatment Diabetic Retinopathy Study) at 1-week, 2-week, and monthly follow-up visits.
No retinal damage was visible ophthalmoscopically during treatment. At the first follow-up visit, seven eyes had obliteration of CNV and one eye required a second TTT application. VA was unchanged in six eyes, improved in one eye, and worsened in one eye. Recurrences occurred in all eyes between 1 and 7 months after TTT and were treated with photodynamic therapy (PDT). More than two PDT treatments were performed in each eye in the year after recurrence.
Low power TTT is as able to close juxtafoveal recurrent CNV as is high power conventional laser photocoagulation but does not prevent recurrences. Further intervention with TTT in order to treat recurrences is under investigation.
Keywords
Aged, Choroidal Neovascularization/etiology, Choroidal Neovascularization/therapy, Coloring Agents, Female, Fluorescein Angiography, Follow-Up Studies, Fovea Centralis, Humans, Hyperthermia, Induced/methods, Indocyanine Green, Low-Level Light Therapy, Macular Degeneration/complications, Male, Pupil, Recurrence, Visual Acuity
Pubmed
Web of science
Create date
11/03/2021 18:07
Last modification date
26/03/2021 7:35
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