Dexamethasone versus diclofenac sodium eyedrops to treat inflammation after cataract surgery.

Details

Serval ID
serval:BIB_B2ED3C3C42C1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Dexamethasone versus diclofenac sodium eyedrops to treat inflammation after cataract surgery.
Journal
Journal of cataract and refractive surgery
Author(s)
Othenin-Girard P., Tritten J.J., Pittet N., Herbort C.P.
ISSN
0886-3350 (Print)
ISSN-L
0886-3350
Publication state
Published
Issued date
01/1994
Peer-reviewed
Oui
Volume
20
Number
1
Pages
9-12
Language
english
Notes
Publication types: Clinical Trial ; Comparative Study ; Journal Article ; Randomized Controlled Trial
Publication Status: ppublish
Abstract
We compared the postoperative anti-inflammatory effect of diclofenac sodium 0.1% and dexamethasone phosphate 0.1% in a prospective, randomized, double-masked pilot study. Anterior chamber inflammation was evaluated by measuring aqueous flare and cells with a laser flare-cell meter at one, three, 12, 30, and 60 days after cataract surgery. Flare values in the two groups did not significantly differ at any time, nor did aqueous cell counts at one, three, 12, and 60 days after surgery. At 30 days, however, cell count was significantly lower in the diclofenac group. Diclofenac sodium seems to be as potent as dexamethasone phosphate, as good as anti-inflammatory agent, and may replace corticosteroid therapy after cataract surgery.
Keywords
Administration, Topical, Aged, Aged, 80 and over, Aqueous Humor/cytology, Aqueous Humor/metabolism, Cataract Extraction/adverse effects, Cell Count, Dexamethasone/administration & dosage, Dexamethasone/therapeutic use, Diclofenac/administration & dosage, Diclofenac/therapeutic use, Double-Blind Method, Endophthalmitis/etiology, Endophthalmitis/prevention & control, Female, Humans, Lenses, Intraocular, Male, Middle Aged, Prospective Studies
Pubmed
Web of science
Create date
06/08/2018 9:04
Last modification date
20/08/2019 15:21
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