Meningite purulente aigue a Listeria seeligeri chez un adulte immunocompetent. [Acute purulent Listeria seelingeri meningitis in an immunocompetent adult]
Details
Serval ID
serval:BIB_B254D0E85D5E
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Meningite purulente aigue a Listeria seeligeri chez un adulte immunocompetent. [Acute purulent Listeria seelingeri meningitis in an immunocompetent adult]
Journal
Schweizerische Medizinische Wochenschrift
ISSN
0036-7672
Publication state
Published
Issued date
02/1986
Peer-reviewed
Oui
Volume
116
Number
8
Pages
248-51
Notes
Case Reports
English Abstract
Journal Article --- Old month value: Feb 22
English Abstract
Journal Article --- Old month value: Feb 22
Abstract
Within the genus Listeria, the species L. monocytogenes most frequently causes disease in animals and humans. L. Seeligeri, a species recently described, has been considered experimentally nonpathogenic so far. The authors report the first case of human infection in a previously healthy adult presenting with acute purulent meningitis due to L. seeligeri. The patient recovered promptly after a course of ampicillin and gentamicin, but developed severe neurological sequelae (epilepsy, hydrocephalus) one year after the acute episode. The pathogenic properties of this isolate were investigated in two experimental animal models and the results were as follows. The clinical isolate of L. seeligeri was able to colonize the spleens of adult mice without bacterial multiplication, in contrast to the type strain of L. seeligeri (no colonization) and to a L. monocytogenes strain (colonization and multiplication). Previous infection of adult mice with the clinical L. seeligeri isolate protected moderately against spleen colonization and bacterial multiplication after challenge with L. monocytogenes. No lethal effect was observed after inoculation of suckling mice with the clinical L. seeligeri isolate, in contrast to L. monocytogenes strains. Thus, L. seeligeri, previously described as experimentally nonpathogenic for mice, may in fact be a heterogeneous species regarding its pathogenicity, and include strains that may cause life-threatening diseases in humans.
Keywords
Humans
Immunocompetence
Listeria monocytogenes/classification
Male
Meningitis, Listeria/immunology/*microbiology
Middle Aged
Suppuration/microbiology
Pubmed
Web of science
Create date
11/02/2008 13:40
Last modification date
20/08/2019 16:21