Crosstalk between neutrophils and dendritic cells: a context-dependent process.

Details

Serval ID
serval:BIB_B1A609D3DF26
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Crosstalk between neutrophils and dendritic cells: a context-dependent process.
Journal
Journal of Leukocyte Biology
Author(s)
Schuster S., Hurrell B., Tacchini-Cottier F.
ISSN
1938-3673 (Electronic)
ISSN-L
0741-5400
Publication state
Published
Issued date
2013
Volume
94
Number
4
Pages
671-675
Language
english
Abstract
Neutrophils are massively and rapidly recruited following infection. They migrate to the site of acute infection and also transiently to dLNs. In addition to their well-established role as microbial killers, accumulating evidence shows that neutrophils can play an immunoregulatory role. Neutrophils were recently shown to influence the activation of different leukocyte types including NK cells, B cells, and DCs. DCs are professional APCs playing a key role to the launching and regulation of the immune response; thus, crosstalk between neutrophils and resident or newly recruited DCs may have a direct impact on the development of the antigen-specific immune response and thereby, on the outcome of infection. Neutrophils may regulate DC recruitment and/or activation. We will review here recent progress in the field, including those presented during the first international symposium on "Neutrophil in Immunity", held in Québec, Canada, in June 2012, and discuss how neutrophil regulatory action on DCs may differ depending on the type of invading microorganism and local host factors.
Keywords
Animals, Cell Communication/immunology, Cell Movement/immunology, Dendritic Cells/cytology, Dendritic Cells/immunology, Humans, Infection/immunology, Infection/pathology, Inflammation/immunology, Inflammation/pathology, Neutrophils/cytology, Neutrophils/immunology
Pubmed
Web of science
Open Access
Yes
Create date
07/01/2014 15:17
Last modification date
20/08/2019 16:20
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