Protein structure computing in the genomic era.
Details
Serval ID
serval:BIB_B19021B39358
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Protein structure computing in the genomic era.
Journal
Research in microbiology
ISSN
0923-2508 (Print)
ISSN-L
0923-2508
Publication state
Published
Issued date
03/2000
Peer-reviewed
Oui
Volume
151
Number
2
Pages
107-112
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
Functional analysis of the proteins discovered in fully sequenced genomes represents the next major challenge of life science research. Computational methods play a crucial role in this activity and, among them, comparative protein modelling is of great assistance during the rational design of mutagenesis experiments. Our aim over the last several years has been to further the use of 3-D model structures in this field. Therefore, we have developed a comparative protein modelling environment composed of the Swiss-PdbViewer (sequence to structure workbench and viewing program), SWISS-MODEL (internet-based server for model generation) and a database of a model generated with 3DCrunch.
Keywords
Computational Biology, Computer Simulation, Databases, Factual, Genome, Genomics, Internet, Models, Molecular, Protein Conformation, Proteins/chemistry, Software
Pubmed
Web of science
Create date
29/01/2021 16:11
Last modification date
30/01/2021 7:26
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