Detrusor bladder neck dyssynergia revisited.

Details

Serval ID
serval:BIB_B12D7767F745
Type
Article: article from journal or magazin.
Collection
Publications
Title
Detrusor bladder neck dyssynergia revisited.
Journal
Journal of Urology
Author(s)
Schurch B., Yasuda K., Rossier A.B.
ISSN
0022-5347 (Print)
ISSN-L
0022-5347
Publication state
Published
Issued date
1994
Volume
152
Number
6 Pt 1
Pages
2066-2070
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
To our knowledge, direct measurement of active closure of the bladder neck during bladder contraction resulting in bladder neck dyssynergia and outflow obstruction has not yet been demonstrated. A total of 34 spinal cord injury patients underwent urodynamic investigation with 2 micro-transducer catheters in the urethrovesical and anorectal regions, respectively. Proper localization of the transducers was done with an image intensifier. The respective role of the striated and smooth muscles on bladder neck activity was evaluated after pudendal nerve blocks and phentolamine injections. Of the patients 25 had active bladder neck dyssynergia with concomitant detrusor-sphincter dyssynergia. Pressures were higher in the bladder neck than in the bladder. Pudendal blocks abolished detrusor-sphincter but not bladder neck dyssynergia, which was decreased by additional phentolamine but only in patients in whom bladder neck dyssynergia was associated with autonomic hyperreflexia. Evidence is presented that active bladder neck dyssynergia may exist in patients with a neurogenic bladder and that it is seemingly dependent on alpha 1-postsynaptic and alpha 2-presynaptic adrenoreceptors.
Keywords
Female, Humans, Male, Muscle Contraction/physiology, Muscle, Smooth/physiopathology, Spinal Cord Injuries/physiopathology, Urinary Bladder/physiopathology, Urodynamics
Pubmed
Web of science
Create date
05/11/2014 13:12
Last modification date
03/03/2018 20:36
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