Contrast-enhanced color Doppler ultrasound characteristics in hypervascular breast tumors: comparison with MRI.
Details
Serval ID
serval:BIB_AE66FC676A0D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Contrast-enhanced color Doppler ultrasound characteristics in hypervascular breast tumors: comparison with MRI.
Journal
European Radiology
ISSN
0938-7994
Publication state
Published
Issued date
2001
Peer-reviewed
Oui
Volume
11
Number
6
Pages
970-977
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Abstract
The aim of this study was to evaluate the accuracy of contrast-enhanced color Doppler ultrasound (CE-US) in comparison with contrast-enhanced MR imaging (CE-MRI) in the discrimination of hypervascularized breast tumors. An additional CE-US of the breast was preoperatively performed in 40 patients with a hypervascular breast lesion detected on CE-MRI. The presence of blood flow signals and the morphological characteristics of the vessels in the breast lesions were evaluated pre- and post-contrast administration, as well as the dynamic aspects of the Doppler signal, including time interval to maximum signal enhancement and persistence of the signal enhancement. Twenty-three carcinomas and 17 fibroadenomas were explored. Considering initial signal enhancement > 100% after the administration of contrast material as a criterion suggesting malignancy, CE-MRI showed a sensitivity of 100% and a specificity of 76.5% in the detection of malignant breast tumors. Color Doppler signals were consistently demonstrated in all carcinomas and in 68.7% of fibroadenomas after the administration of Levovist, with CE-US showing a sensitivity of 95.6% and a specificity of 5.9%. Neither the mean number of vessels per tumor, nor the location of vessels, the time to maximum increase of the Doppler signal or the persistence of signal enhancement showed significant differences between benign and malignant lesions. Additional CE-US does not increase the low specificity of MRI in patients with hypervascularized breast tumors.
Keywords
Adult, Aged, Breast Neoplasms/blood supply, Breast Neoplasms/diagnosis, Carcinoma, Ductal, Breast/blood supply, Carcinoma, Ductal, Breast/diagnosis, Carcinoma, Intraductal, Noninfiltrating/blood supply, Carcinoma, Intraductal, Noninfiltrating/diagnosis, Contrast Media, Diagnosis, Differential, Female, Fibroadenoma/blood supply, Fibroadenoma/diagnosis, Gadolinium DTPA/diagnostic use, Humans, Image Enhancement, Magnetic Resonance Imaging, Middle Aged, Neovascularization, Pathologic/diagnosis, Polysaccharides/diagnostic use, Predictive Value of Tests, Ultrasonography, Doppler, Color
Pubmed
Web of science
Create date
08/04/2008 16:47
Last modification date
20/08/2019 16:18